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Free radicals, like reactive oxygen species (ROS) and reactive nitrogen species (RNS), are naturally occurring, toxic compounds that are formed when the body converts food to energy

8 This effect increased with duration of therapy, and patients had an unclear prophylactic supplementation response

On examining his blood smear, he noticed many bizarrely shaped red blood cells, leading him to surmise that the cause of the disease may be some unrecognized change in the red corpuscle itself (Herrick, 2014)

Metabolomics analysis Targeted metabolomics was performed as described previously 23

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