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7.4 IGF-1 induces cell differentiation Current regenerative research has focused on the studies of growth factor supplementation that can induce stem cells into tenogenic lineage for an alternative cell source to replenish functional tendon cells at the injured site ( in vitro culture with significant upregulation of tenocytic markers (SCX, collagen type III, and decorin) ( in vivo data are available regarding the efficacy of exogenously delivery of IGF-1 in combination with stem cells to treat tendon injury
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Some individuals may also combine glutathione with vitamin C for enhanced antioxidant effects, based on professional advice
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