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Direct SlC7A11 overexpression in cardiac myocytes boosted GSH levels and reduced cardiac ferroptosis and injury, suggesting that it is feasible to fortify GSH levels by increasing SLC7A11 [76]

Over time, the skin-lightening effect faded: by 6-month follow-up, only 1 out of 16 maintained visible benefit

These temperature-sensitive peptide medicationsincluding semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)require specific storage conditions to maintain therapeutic effectiveness

For example, EA was conjugated to 2-amino-2-deoxy-d-glucose (EAG) 90 , obtaining an adduct with significant anticancer activity such as EA but without the undesired diuretic activity 90