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Vafa O, Wade M, Kern S, Beeche M, Pandita TK, Hampton GM, Wahl GM: c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP 1LC3B and ATG5