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Although we felt the homogenization method may be acceptable for labs with the facilities to make the particles and that these experiments allowed us to optimize the parameters necessary for protein purification, we felt that further improvements were possible
The oral form is formulated at a higher dose than the injectable version to account for what is lost during digestion and to ensure the medication is fully absorbed at therapeutic levels
However, substrate concentrations will vary over time, such that relevant values would be difficult to assess
J Diabetes Complications (2013) 27:26873
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