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Budur, J
published in 2025)
the hyperphosphorylation of tau proteins leads to the disruption of microtubule structure and affects mitochondrial axonal transport, exacerbating the neuronal energy crisis (Meng et al., 2024)
The first nootropic to use the term was a drug developed in the 1960s called piracetam.60 61 It was intended to treat anxiety and provide patients with a soothing experience that might even lull them to sleep.2 The effect was quite different than what its creators intended, as users reported sharper focus, and later testing pointed toward improved memory
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