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Kidney and heart failure outcomes associated with SGLT2 inhibitor use
This can help improve cardiovascular fitness, reduce blood pressure, and maintain a healthy weight
The primary mechanism is gastric emptying delay
( Epub 20210415 )
Indeed, eGFR values were greater in patients on tirzepatide compared to those on insulin glargine, with a mean eGFR decline rate of 1.4 ml/min/1.73 m 2 per year in tirzepatide users and a between-group difference in eGFR reduction of 2.2 ml/min/1.73 m 2 per year [49]
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