Unlike natural ghrelin, it does not significantly increase appetite , allowing controlled GH release
Alam M, Hughart R, Champlain A, et al
Results Disclaimer: Individual results from GLP-1 weight loss treatment vary based on factors including age, baseline health condition, metabolic profile, consistency of use, dietary habits, physical activity levels, genetic factors, and adherence to clinical guidance
The strongest, clearest evidence is biochemical: growth hormone releasing compounds like CJC-1295 raise growth hormone and IGF-1, and studies of growth hormone secretagogues confirm they can increase IGF-1, a measurable marker on the pathway (a 2017 study showing a growth hormone secretagogue raised serum IGF-1)
And as discussed below, NAD+ is not recommended for women who are pregnant or breastfeeding