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Funding The author(s) declare that financial support was received for the research, authorship, and/or publication of this article

The peptides for testosterone and testosterone peptide resources address compounds that specifically target testosterone support, which may complement metabolic peptides in men with documented deficiency

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Together, this work provides a proteome-wide profile of arginine reactivity and ligandability, offering insights into the functional landscape of arginines and expanding the scope of covalent drug discovery to include arginine-targeting molecules