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Resistance training remains essential regardless of dietary approach

While adenosine triphosphate (ATP) signaling was enhanced, capsaicin sensitivity was unaffected by the acute application of exendin-4 in cultured DRG neurons, suggesting GLP-1R role in modulating gut motility rather than pain signaling

Bottom Line Ozempic, Wegovy, and Mounjaro are all effective medications, but they are designed for different goals

These wont replace training or substitute for GLP-1 in Charleston, but they can support adherence and results, especially for those with sedentary lifestyles or physical limitations

Ongoing medical supervision and monitoring are essential for long-term safety