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Analysis based on information available as of December 26, 2025
The prevalence rates in Europe, China, and North America were close to 1.5%, but significant variations exist between different regions and populations
Side Effects: Side effects are uncommon but may include pain at the injection site, nausea, and fatigue/dizziness
Yamaji, M
In contrast, integral membrane substrates with degrons present in TMDs or within cytoplasmic domains are recognized by HRD1 in an ER lectin-independent manner or by other ERAD E3 ubiquitin ligases equivalently or preferentially
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