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Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome

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Nonclinical programs should include organ-system panels, cardiovascular telemetry where appropriate, and full pathology review to characterize off-target consequences of chronic ERR activation

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These figures show why the two vials are documented at different per-dose amounts: the 20 mg vial is set up to last far longer per vial

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