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demonstrated that the lactylation of NBS1 can promote the formation of the MRN complex and homologous recombination-mediated DNA repair, thereby mediating the chemoresistance of tumors

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However, rising antibiotic resistance has reduced eradication rates, with recent rates falling below 80% in many countries (Tshibangu-Kabamba and Yamaoka, 2021), necessitating the development of novel therapeutic strategies

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