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received honoraria as a speaker for AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly, Elpen, Galenica, GSK, MSD, Mylan, Novartis, Novo Nordisk, Pfizer, Sanofi Aventis, Takeda and Vianex

In many cases these reactions are mild and improve without additional treatment, although patients should continue monitoring the area and report persistent or worsening symptoms to their healthcare provider