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For a broader overview of how these therapies work, see how GLP-1 actually supports weight loss

Given that chemokine upregulation can result in chronic inflammation associated with onset and progression of age-related neurodegenerative diseases such as AD, our study employed MCP-1 staining in the frontal cortex and the hippocampus to assess the extent of possible inflammatory reactivity to amyloid plaques and microglial activity [23-25]

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Figure 35: Diagram showing action of GLP-1, GIP (incretins) and DPP-4 inhibitors, credit: Ilmari Karonen, Wikimedia