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Currently, a clinical trial of E6011 (an anti-CX3CL1 mAb) has been demonstrated to have a promising role in active RA patients ( ( Figure 2 )
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Notably, this system includes both eNOS phosphorylation and NO release
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10.1016/j.regpep.2012.12.007 7 BecejacT.CesarecV.DrmicD.HirslD.MadzaracG.DjakovicZ.et al (2018)
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