They rarely test MOTS-c as a direct medical treatment
Numerous cell signaling pathways are involved in the initiation and progression of cancer cachexia, including the TNF- pathway, TGF/p38/MAPK pathway, NFB pathway, IL-6 pathway, IGF/Akt pathway and FOXO1/FOXO3a pathway, among others [44]
At 48 h post-injection, the mice were euthanized to collect tumors and major organs for subsequent ex vivo imaging
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Adsorption experiment The relative difference in the TMB adsorption capability of pFeSAN and FeSAN was determined by the obvious UV-vis absorption peak of TMB at 285 nm