Notably, these three independent reportsalthough referring to only fifteen casesreciprocally strengthen each other in highlighting the relevance of poor GSH levels in COVID-19 clinical progression as well as the importance of maintaining/repleting GSH pools as a countermeasure against SARS-CoV2 virulence
If any of these happen, make sure you reach out to your healthcare provider immediately
One study published in the Journal of Rheumatology found that lupus patients had significantly lower levels of glutathione compared to healthy controls
In published preclinical work, KPV has been studied for inhibiting NF-B activation in intestinal epithelial cells, with one widely cited study showing PepT1-mediated transport into colonic cells as part of its anti-inflammatory mechanism in mouse colitis models (Dalmasso et al., Gastroenterology , 2008)
Oral glutathione supplements, for instance, offer a non-invasive option