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This data is consistent with the promising weight-loss data of GLP-1 agonists

Previous research discovered that the Cu-overload can lead to proteotoxic stress and bacterial cuproptosis-like death by inducing lipid peroxidation accumulation and disrupting the respiratory chain [36]

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Subgroup analyses evaluated four key factors: administration route efficacy, daily dosage, age group and clinical conditions that may affect vitamin B12 metabolism (e.g., underlying pathology)