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Some people do experience chest tightness

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[3] Hypothalamic-Pituitary-Adrenal (HPA) Axis Modulation : DSIP has been observed to attenuate stress-induced corticotropin-releasing hormone (CRH) activity, potentially reducing systemic cortisol release

Protection of vascular endothelial cells from hydrogen peroxide-induced oxidant injury by gypenosides, saponins of Gynostemma pentaphyllum

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