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During the pathogenesis of OA, JUN directly binds to the promoter of NCOA4 and initializes its transcription, increasing ferritinophagy degradation, leading to ferroptosis and extracellular matrix degradation in chondrocytes
Adding more copper on top defeats the precision-delivery mechanism and increases free copper exposure
Effect of chronic handling and social isolation on emotion and cognition in adolescent rats
In advanced cases with borderline resectable disease, patients could potentially receive therapies before the surgery to increase the chances of successful surgical removal of the tumor
Immunity (2014) 40(5):692705
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