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Part 1 of 2 covers the mechanism and the U/kg trend, the portal-peripheral mismatch, and the Ominous Octet framework
For example, some individuals may require more frequent follow-ups in the beginning to ensure the treatment is well-tolerated
Treatment plans must include clear duration guidelines and exit strategies, with particular attention to muscle mass preservation throughout the course of therapy
In contrast, the SMR method has a narrower 95% CI, potentially suggesting higher accuracy although its OR value approaches 1
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