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As expected from previous studies (25), leptin administration significantly reduced food intake and body weight in fasted WT controls (Figure 4, C and E)

doi:10.1074/jbc.M004838200

Das bedeutet: Der Krper muss diese entweder selbst in ausreichender Menge bilden oder sie mssen ber die Ernhrung zugefhrt werden

Further studies did find that butyrate can increase the expression of peroxisome proliferatoractivated receptor (PPAR)- coactivator-1(PGC-1) (116), which is a critical regulator of mitochondrial function, and stimulates thermogenesis via the upregulation of UCP1 expression (149)

Retrieved May 12, 2025, from Nguyen, M., & Tadi, P