A simple 25 OH D blood test can be ordered to monitor vitamin D levels
To date, observational studies investigating the cardiovascular effectiveness of the combination have either been underpowered or had important methodological limitations, such as immortal time bias.1215181920 Importantly, none compared the combination with either drug class alone or investigated serious renal events, which are clinically relevant outcomes in this patient population.1215181920 The primary objective of this study was to determine whether the combined use of GLP-1 receptor agonists and SGLT-2 inhibitors is associated with a decreased risk of two co-primary outcomes, major adverse cardiovascular events and serious renal events, compared with the use of either drug class alone among patients with type 2 diabetes
Cochran AJR, Myslik F, MacInnis MJ, et al
While it has also proven to be effective for weight loss, its weight-reducing effects may not be as pronounced as those seen with tirzepatide
In metabolically healthy men, an infusion of Bay 27-9955, one of the first small-molecule GcgR antagonists, lowered blood glucose in response to a glucagon challenge [53]