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Cycle Length: 48 weeks, followed by a break

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Distinguishing Between Expected Side Effects and True Depression Common, expected side effects of tirzepatide include nausea, loss of appetite, and changes in taste preference

Two of three subjects who had insulin resistance at baseline showed normal insulin responsiveness at the end of the study, and highly sensitive C-reactive protein (hs-CRP, a marker of systemic inflammation) improved by a median of 25% among participants who showed clinical psoriasis improvement