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Elevated Cortisol and Prolactin Levels: May result in stress-related symptoms, decreased libido, and gynecomastia in men
Research suggests these applications may give insights into preserving muscle function across various challenge conditions
Lips -- Abnormalities Medical Subject Pathology, Oral
It is therefore unsurprising that the LD 50 values for compounds 1 and 2 determined ex vivo have a similar discordance to that seen for PZQ when considering in vivo PK/PD: much like PZQ these compounds are schistosomicidal in vivo at sub LD 50 concentrations
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