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In another cost-effectiveness analysis done for the UK market, orally administered semaglutide 14 mg was found to be cost effective relative to sitagliptin 100 mg and empagliflozin 25 mg and dominant in comparison to liraglutide 1.8 mg daily dose for the treatment of T2DM
With a half-life of 5 days, it requires 4-5 half-lives for the medication to be largely cleared, though trace amounts may persist slightly longer in some individuals
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