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Eur Rev Med Pharmacol Sci (2019) 23(5):1899906
[67] [68] Epidemiology [edit] PA is estimated to affect 0.1% of the general population and 1.9% of those over 60, accounting for 2050% of B 12 deficiency in adults
230 Webster and Maggio also noted that patients with large capacities under anesthesia were more likely to fail
While anyone with a B12 deficiency can benefit from injections, certain groups are more likely to require this treatment, including vegetarians and vegans who may not consume enough B12-rich foods, individuals with digestive disorders like Crohns disease or coeliac disease, those with pernicious anaemia that affects B12 absorption, people recovering from weight loss surgery or other gastrointestinal procedures, older adults whose ability to absorb B12 decreases with age, and individuals experiencing prolonged fatigue or low energy levels
Just at reduced bioavailability (approximately 3540% lower than fasted-state dosing)
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