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Support botanicals: Grape seed extract, eleuthero root, astragalus root, gymnema sylvestre, coleus forskohlii, and grapefruit seed provide broad-spectrum metabolic, digestive, and anti-inflammatory support

Venous blood samples were obtained after patients had fasted overnight (12 h)

Changes in HbA1c in participants with pre-existing pre-diabetes between treatment arms, and in participants with pre-existing T2D between treatment arms, was assessed with the inclusion of an interaction term between diabetes status and treatment allocation in the linear regression model for HbA1c and calculated from estimated marginal means

Adequate protein intake helps maintain muscle mass during calorie restriction associated with weight loss