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Deamidation, oxidation, and aggregation explained Deamidation is the most common degradation pathway for peptide therapeutics

The titration phase (first 1620 weeks) is focused on reaching the therapeutic dose while minimizing GI side effects, not on maximum weight loss which is why early results are often modest

With effectiveness beyond diabetes and obesity, Noom is leveraging Big Pharmas declaration of GLP-1s as longevity medicinewhile prescribing minimal effective dosesto normalize the treatment and supercharge its platforms outcomes

Just like a diet, eventually weight will be lost, but a frequent concern is the loss of lean muscle mass during treatment