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(2017) MicroRNA-153 regulates glutamine metabolism in glioblastoma through targeting glutaminase, Tumour Biol

Doses greatly exceeding the nutritional requirements (for example, hundreds of milligrams daily) have not been studied in randomized trials for safety, so one should avoid mega doses in pregnancy unless treating a specific condition (such as pyridoxine-responsive seizures) under careful supervision

A 2021 study in Nature Communications showed MOTS-C improves skeletal muscle metabolism and helps preserve muscle homeostasis, especially during caloric deficits

This is essentially whats behind the hype, in so many gut-focused supplement protocols

[PMID: 7329316] PubMed record related to this compound for laboratory literature review