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SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle

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Survodutide# Survodutide (BI 456906) is a dual agonist that activates both the GLP-1 receptor and the glucagon receptor (GCGR), with an activity ratio favoring glucagon receptor activation approximately 4-5 fold over GLP-1R