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The combination of low intracellular GSH levels and low expression of ABCC1 and ABCC2 in proliferative endothelial cells accounts for GSAO selectivity and subsequently for GSAO anti-angiogenic properties (Dilda et al., 2005a,b

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However, highly sensitive preoperative and intraoperative diagnosis of tumor remains a challenge for the above imaging modalities, primarily due to their limited resolution, potential radiation exposure risks, and inability to offer timely feedback on treatment outcomes during surgery [7], [8]

10.1039/b602976k J