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found that the ratio of ERS-activated pro-apoptotic protein CHOP to anti-apoptotic protein ORP150 increased under long-term HG conditions (after 16 weeks), leading to apoptosis (44)
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In published research protocols, BPC-157 has been studied across a dosing range of 1-10 mcg/kg in animal models, with the majority of positive results observed at doses between 2-10 mcg/kg administered intraperitoneally or subcutaneously
10.1371/journal.pone.0129146 32
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