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also reported that treatment with liraglutide (0.6 3 mg daily) in seven patients with PWS (in combination with topiramate in 3 individuals), resulted in a variable response with a median weight loss of 9 kg over 96 weeks (37)

Because of this multi-receptor approach, early data on Retatrutide has shown higher average body weight reduction compared to single-agonist treatments like Ozempic