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BMC Medicine , 2025
A larger clinical trial randomly assigned more than 500 patients with type 2 diabetes and symptomatic peripheral neuropathy to one of the following treatments: (i) 600 mg/day of intravenous lipoic acid for three weeks followed by 1,800 mg/day of oral lipoic acid for six months, (ii) 600 mg/day of intravenous lipoic acid for three weeks followed by oral placebo for six months, or (iii) intravenous placebo for three weeks followed by oral placebo for six months (76)
Sourcing matters more than branding here, and a compounding pharmacy operates under a different regulatory framework again, which is worth knowing when comparing where material comes from
Some polymorphic UGTs have demonstrated a significant pharmacological impact in addition to being relevant to drug-induced adverse reactions and cancer susceptibility
This study holds significant value by demonstrating, through large-scale population data, the potential for metabolic disease treatments to contribute to brain health and the prevention of neurological disorders in a field where preventive strategies have been limited
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