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Body composition matters more than body weight
The concentration of purified At LDOX was measured with a NanoDrop spectrophotometer (Thermo Fisher Scientific) at A 280nm using an extinction coefficient estimated with ProtParam 50
While healthy fat tissue contains beneficial immune cells, excess weight transforms it into an inflammatory factory, releasing pro-inflammatory mediators like TNF-, IL-6, and free fatty acids
Antidiabetic drugs, including intranasally administered insulin, as well as GLP-1RAs, modify the processes linking T2DM with cognitive impairment [29]
Each of the four components is individually verified at 99% purity via HPLC analysis before blending
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