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The Mayo Clinic shares that those most at risk of low levels include (5): people who dont consume enough vitamin B12 in their diet people diagnosed with pernicious anemia people whove had gastric surgeries people with intestinal issues, such as celiac or Crohns disease People following a vegetarian diet are especially at risk of deficiency

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The BBB mechanisms and functions The main physiological roles of the BBB include providing nutrients to the brain and maintaining ionic balance, shielding the brain from external neurotoxins, and regulating neurotransmitter levels

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