These findings are from animal models and cell culture studies
If a patients body is already producing GLP-1 at normal or elevated levels, prescribing a long-acting agonist isnt correcting a deficit
Most experts recommend combining GLP-1 drugs with improved nutrition, increased physical activity, reduced sedentary behavior, stress management and other healthy habit changes
Research involving individuals with type 1 diabetes, meanwhile, demonstrated that subcutaneous glucagon-like peptide-1 administration before meals led to decreased postprandial glucose excursions and suppressed glucagon levels without increasing the risk of hypoglycemia
Early data also suggest potential benefits in liver disease, obstructive sleep apnea, chronic respiratory disorders, neurodegenerative and psychiatric conditions, reproductive dysfunction, obesity-associated cancers, and sepsis, although these remain investigational