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In that case, stop using the product right away (if its a topical, gently wash it off with cool water) and seek prompt medical attention

Available from: What is berberine and why should I take it

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TLR4 activation may lead to ROS signaling via direct interaction between TLR4 and NADPH oxidase (Gill et al., 2010

Research also suggests that individuals who experienced severe sunburn after more than two hours of sun exposure in childhood have an increased risk of developing vitiligo