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Additionally, the membrane expression of TfR1 is positively regulated by PKC phosphorylation, which in turn promotes iron uptake
Post hoc analysis of its placebo-controlled trial in patients with non-alcoholic steatohepatitis (NCT00227110) demonstrated that pioglitazone reduces hepatic/visceral fat and improves necrosis and inflammation (113)
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The top five precursor ions were subsequently fragmented, in a data-dependent manner, using the higher energy collisional dissociation cell set to 30% normalized collision energy in MS2 at a resolution power of 17,500
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