Elliptozytose - Labrador Retriever Hundebesitzer-Featured Specific A-Locus allele products can

Specific A-Locus allele products can interact with functional MC1R and thus interfere with production of black melanin

if other loci are expressed (B

Daher könnte der Gesamtgenotyp des B-Lokus für einen Hund B/b oder b/b sein (der Hund kann schwarz oder braun erscheinen) und kann vom Labor ohne zusätzliche Tests der Eltern nicht bestimmt werden

DLA genes (DLA-DRB1

Examination material: oral mucosa swabs or 1-2 ml EDTA blood

Elliptozytose - Labrador Retriever Hundebesitzer-Featured Specific A-Locus allele products canElliptocytosis is an autosomal disorder of the red blood cells (RBC), which assume an elongated elliptical shape rather than typical round shape. The condition is diverse, ranging from asymptomatic cases to severe haemolysis. Clinical signs include severe haemolytic anaemia, loss of the normal elastic recoil property of RBCs within the peripheral circulation, resulting in their distinctive elliptical shape. This disturbance is caused because the