B-Lokus (Australian Shepherd) DNA-Profil Dry eye curly coat syndrome

Dry eye curly coat syndrome (CKCSID) is a hereditary disease that can be tested with a DNA test

was zu einem nicht funktionalen Protein führt

Es besteht jedoch ein potenziell höheres Risiko

which leads to a cerebellar dysfunction that results in uncoordinated movements and intention tremor

Mutation: upstream of GDNF gene

B-Lokus (Australian Shepherd) DNA-Profil Dry eye curly coat syndromeGene TYRP1 (Tyrosinase related protein 1) is responsible for chocolate liver brown colour in dogs. This coat colour is inherited recessively. There are 4 different variants on B Locus in Australian Shepherds: bc, bs, bd and baus. Combination of any two recessive alleles will result in chocolate liver brown colour (for example two bc alleles or one bc and one bs allele). Because TYRP1 gene is related to eumelanin production, it only affects dogs which