Neuronale Zeroidlipofuszinose 8 (NCL-8) - Alpenländische Dachsbracke Diversität Hereditary ataxia shows symptoms of

Hereditary ataxia shows symptoms of slow degeneration of the cerebellar cortex

The majority of puppies affected with NCCD are euthanized shortly after diagnosing the first signs of this disease

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The symptoms are only present in bright light

Mutation: CCDC39 gene

Neuronale Zeroidlipofuszinose 8 (NCL-8) - Alpenländische Dachsbracke Diversität Hereditary ataxia shows symptoms ofNeuronal ceroid lipofuscinoses (NCLs) are a group of heritable diseases characterized by progressive neuronal degeneration and the accumulation of autofluorescent cytoplasmic inclusions in the brain, retina and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate