MCAD-Mangel Züchter which leads to a cerebellar

which leads to a cerebellar dysfunction that results in uncoordinated movements and intention tremor

frizzy and alopecic coat is evident in the first few months of life

spontan auftretende

Der Test für den B-Lokus ist in drei separate Tests unterteilt

Mutation: BEST1 gene

MCAD-Mangel Züchter which leads to a cerebellarMedium Chain Acyl CoA Dehydrogenase Deficiency (MCAD deficiency) is an autosomal recessive hereditary disease described in Cavalier King Charles Spaniels. It is characterized by defect of MCAD enzyme that is crucial for metabolism of medium chain fatty acids (MCFAs) that serve as energy source for the body. In MCAD deficient individuals, unmetabolized MCFAs accumulate in different tissues, resulting in insufficient production of energy out of ketone