Progressive Retinaatrophie (PRA-BBS2) evg-analysen degenerative disorders characterized by progressive

degenerative disorders characterized by progressive muscular dysfunction

In the chronic type

Mutation: MCHR2 gene

Clinical signs appear at just few weeks after birth

Before an episodic seizure

Progressive Retinaatrophie (PRA-BBS2) evg-analysen degenerative disorders characterized by progressiveProgressive retinal atrophies (PRA) are a group of hereditary diseases characterized by vision impairment due to retinal degeneration, which is a result of progressive cell death of the rod and cone photoreceptors in the retina. A late onset form of PRA called BBS2 PRA was characterized in Shetland Sheepdogs. Clinical symptoms, which include retinal thinning, atrophy of the optic disc, retinal vascular weakening, night blindness and decline in