Angeborene Augenfehlbildung (CEM) Labrador Retriever Mutation: ACADM gene

Mutation: ACADM gene

Der Test identifiziert Mutationen in den Genen ATP7A (Menkes-Erkrankung) und ATP7B (Wilson-Erkrankung)

It allows expression of A-Locus

Cone Degeneration oder Achromatopsie (ACHM) ist eine angeborene Netzhauterkrankung und kann bei betroffenen Hunden in ihrer Schwere variieren

The symptoms start to show at around 6 months of age and include abnormal bleeding

Angeborene Augenfehlbildung (CEM) Labrador Retriever Mutation: ACADM geneEye Malformations can be caused by environmental or genetic factors. A new form of CEM has been observed in Golden Retrievers with clinical signs including unilateral or bilateral retina dysplasia and or optic nerve hypoplasia. In some severe cases, dogs are euthanized due to bilateral changes, aggressivity, or some other severe clinical signs. A mutation in SIX6 gene has been observed in Golden Retrievers with CEM, suggesting a strong connection