Progressive Retinaatrophie, Rod-cone Dysplasie 4 (PRA-rcd4) ISAG Affected dogs cannot develop antibodies

Affected dogs cannot develop antibodies

Only a genetic test can clarify whether a dog is a Mc carrier

Mutation: MTM1 gene

It occurs in Rhodesian Ridgeback breed

Mutation: AP3B1 gene

Progressive Retinaatrophie, Rod-cone Dysplasie 4 (PRA-rcd4) ISAG Affected dogs cannot develop antibodiesProgressive retinal atrophy (PRA) is an inherited disease that occurs in many breeds of dogs and is reflected in various clinically indistinguishable forms. Progressive rod and cone degeneration in retina leads to progressive vision loss, which ends with total blindness. RCD4 is a form of PRA that was first described in Gordon Setters and later found in several other dog breeds. Gradual photoreceptor cell degeneration is typical for this form of the