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Mutation: VLDLR gene
✔ Comparison with approximately 30
Dogs with cystinuria do not absorb cystine in kidney tubules therefore they have abnormally high urine concentrations of cystine
wird eine Fortschreitung der Krankheit beobachtet
Clinical signs show very rapid progression and puppies are usually euthanized
Osteogenesis Imperfecta (OI) – Chow Chow Katzen Mutation: VLDLR geneOsteogenesis imperfecta (OI) is a hereditary disease characterized by extremely fragile bones and teeth. Clinical signs include pain, spontaneous fractures of bones, teeth fractures, joint hyperlaxity and reduced bone density on radiography. Teeth are very thin and fragile, otherwise normal size. In affected dogs, clinical signs occur within the first few weeks of life. OI is characterized by significant reduction of the formation of bone and tooth
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