Faktor VII Defizienz (FVII) Mischling meaning that the most dominant

meaning that the most dominant allele present will be expressed

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Hereditary necrotising myelopathy (HNM) is an autosomal recessive inherited neurological disease in dogs

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Mutation: PDK4

Faktor VII Defizienz (FVII) Mischling meaning that the most dominantFactor VII (FVII) is a vitamin K dependent coagulation factor. It is synthesized in the liver and secreted into the circulation. It plays a major role in initiation of blood coagulation. Factor VII deficiency is associated with a bleeding tendency. Clinical signs in affected dogs include mild to severe bleeding after trauma or surgery. Inheritance: autosomal recessive Mutation: Coagulation factor VII gene Genetic test: The method used for testing is